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Effect of CDR3 Sequences and Distal V gene Residues in Regulating TCR-MHC contacts and ligand specificity
The mature T cell repertoire has the ability to orchestrate immunity to a wide range of potential pathogen challenges. This ability stems from thymic development producing individual T cell clonotypes that express T cell receptors (TCR) with unique patterns of antigen reactivity. The antigen specifi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097884/ https://ncbi.nlm.nih.gov/pubmed/24813203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303209 |
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