Yüklüyor......
A temporal thymic selection switch and ligand binding kinetics constrain neonatal Foxp3(+) T(reg) cell development
The neonatal thymus generates Foxp3(+) regulatory T (tT(reg)) cells that are critical in controlling immune homeostasis and preventing multi-organ autoimmunity. The role of antigen specificity on neonatal tT(reg) cell selection is unresolved. Here we identify seventeen self-peptides recognized by ne...
Kaydedildi:
| Yayımlandı: | Nat Immunol |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039339/ https://ncbi.nlm.nih.gov/pubmed/31209405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0414-1 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|