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Effect of CDR3 Sequences and Distal V gene Residues in Regulating TCR-MHC contacts and ligand specificity

The mature T cell repertoire has the ability to orchestrate immunity to a wide range of potential pathogen challenges. This ability stems from thymic development producing individual T cell clonotypes that express T cell receptors (TCR) with unique patterns of antigen reactivity. The antigen specifi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Stadinski, Brian D., Trenh, Peter, Duke, Brian, Huseby, Priya G., Li, Guoqi, Stern, Lawrence J., Huseby, Eric S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097884/
https://ncbi.nlm.nih.gov/pubmed/24813203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303209
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