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Hydrophobic CDR3 residues promote the development of self-reactive T cells
Studies of individual T cells receptors (TCRs) have shed some light on structural features that underlie self-reactivity. However, general rules that predict whether TCRs are self-reactive have not been fully elucidated. Analyses of thymocytes expressing all V(β) family members show that the interfa...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955740/ https://ncbi.nlm.nih.gov/pubmed/27348411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3491 |
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