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A drug-inducible system for direct reprogramming of human somatic cells to pluripotency
Current approaches to reprogram human somatic cells to pluripotent iPS cells utilize viral transduction of different combinations of transcription factors. These protocols are highly inefficient because only a small fraction of cells carry the appropriate number and stoichiometry of proviral inserti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097107/ https://ncbi.nlm.nih.gov/pubmed/18786421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.08.014 |
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