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CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy
Radiotherapy is used to treat many types of cancer, but many treated patients relapse with local tumor recurrence. Tumor-infiltrating myeloid cells (TIMs), including CD11b (ITGAM)(+)F4/80 (EMR1)(+) tumor-associated macrophages (TAMs) and CD11b(+)Gr-1 (LY6G)(+) myeloid-derived suppressor cells (MDSCs...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097014/ https://ncbi.nlm.nih.gov/pubmed/23418320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3981 |
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