CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy

Radiotherapy is used to treat many types of cancer, but many treated patients relapse with local tumor recurrence. Tumor-infiltrating myeloid cells (TIMs), including CD11b (ITGAM)(+)F4/80 (EMR1)(+) tumor-associated macrophages (TAMs) and CD11b(+)Gr-1 (LY6G)(+) myeloid-derived suppressor cells (MDSCs...

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Bibliographic Details
Main Authors: Xu, Jingying, Escamilla, Jemima, Mok, Stephen, David, John, Priceman, Saul, West, Brian, Bollag, Gideon, McBride, William, Wu, Lily
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097014/
https://ncbi.nlm.nih.gov/pubmed/23418320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3981
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