CSF1 Receptor Targeting In Prostate Cancer Reverses Macrophage-Mediated Resistance To Androgen Blockade Therapy

Growing evidence suggests that tumor-associated macrophages (TAMs) promote cancer progression and therapeutic resistance by enhancing angiogenesis, matrix-remodeling and immunosuppression. In this study prostate cancer (PCa) under androgen blockade therapy (ABT) was investigated, demonstrating that...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Escamilla, Jemima, Schokrpur, Shiruyeh, Liu, Connie, Priceman, Saul J., Moughon, Diana, Jiang, Ziyue, Pouliot, Frederic, Magyar, Clara, Sung, James L., Xu, Jingying, Deng, Gang, West, Brian L., Bollag, Gideon, Fradet, Yves, Lacombe, Louis, Jung, Michael E., Huang, Jiaoti, Wu, Lily
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359956/
https://ncbi.nlm.nih.gov/pubmed/25736687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0992
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