CSF1 Receptor Targeting In Prostate Cancer Reverses Macrophage-Mediated Resistance To Androgen Blockade Therapy

Growing evidence suggests that tumor-associated macrophages (TAMs) promote cancer progression and therapeutic resistance by enhancing angiogenesis, matrix-remodeling and immunosuppression. In this study prostate cancer (PCa) under androgen blockade therapy (ABT) was investigated, demonstrating that...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Escamilla, Jemima, Schokrpur, Shiruyeh, Liu, Connie, Priceman, Saul J., Moughon, Diana, Jiang, Ziyue, Pouliot, Frederic, Magyar, Clara, Sung, James L., Xu, Jingying, Deng, Gang, West, Brian L., Bollag, Gideon, Fradet, Yves, Lacombe, Louis, Jung, Michael E., Huang, Jiaoti, Wu, Lily
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359956/
https://ncbi.nlm.nih.gov/pubmed/25736687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0992
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