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Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer

Malignant ascites is a common complication in the late stages of epithelial ovarian cancer (EOC) that greatly diminishes the quality of life of patients. Malignant ascites is a known consequence of vascular dysfunction, but current approved treatments are not effective in preventing fluid accumulati...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Moughon, Diana L., He, Huanhuan, Schokrpur, Shiruyeh, Jiang, Ziyue Karen, Yaqoob, Madeeha, David, John, Lin, Crystal, Iruela-Arispe, M. Luisa, Dorigo, Oliver, Wu, Lily
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675660/
https://ncbi.nlm.nih.gov/pubmed/26471360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3373
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