Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy

Tumor-infiltrating myeloid cells (TIMs) support tumor growth by promoting angiogenesis and suppressing antitumor immune responses. CSF-1 receptor (CSF1R) signaling is important for the recruitment of CD11b(+)F4/80(+) tumor-associated macrophages (TAMs) and contributes to myeloid cell-mediated angiog...

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Autors principals: Priceman, Saul J., Sung, James L., Shaposhnik, Zory, Burton, Jeremy B., Torres-Collado, Antoni X., Moughon, Diana L., Johnson, Mai, Lusis, Aldons J., Cohen, Donald A., Iruela-Arispe, M. Luisa, Wu, Lily
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Vascular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826767/
https://ncbi.nlm.nih.gov/pubmed/20008303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-237412
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