Arterial colony stimulating factor-1 influences atherosclerotic lesions by regulating monocyte migration and apoptosis

Previous studies have shown that colony stimulating factor-1 (CSF-1) deficiency dramatically reduced atherogenesis in mice. In this report we investigate this mechanism and explore a therapeutic avenue based on inhibition of CSF-1 signaling. Lesions from macrophage colony stimulating factor-1 (Csf1)...

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Bibliographic Details
Main Authors: Shaposhnik, Zory, Wang, Xuping, Lusis, Aldons J.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882747/
https://ncbi.nlm.nih.gov/pubmed/20194110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M005215
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