Local macrophage colony-stimulating factor expression regulates macrophage proliferation and apoptosis in atherosclerosis

OBJECTIVE: Previous studies have shown that deficiency of macrophage colony-stimulating factor (M-CSF or CSF1) dramatically reduces atherosclerosis in hyperlipidemic mice. We characterize the underlying mechanism and investigate the relevant sources of CSF1 in lesions. APPROACH AND RESULTS: We quant...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Sinha, Satyesh K., Miikeda, Aika, Fouladian, Zachary, Mehrabian, Margarete, Edillor, Chantle, Shih, Diana, Zhou, Zhiqiang, Paul, Manash K, Charugundla, Sarada, Davis, Richard C., Rajavashisth, Tripathi B., Lusis, Aldons J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769919/
https://ncbi.nlm.nih.gov/pubmed/33086870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315255
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