Restoration of PTEN Activity Decreases Metastases in an Orthotopic Model of Colon Cancer

BACKGROUND: Mutational loss of tumor suppressor phosphatase and tensin homologue deleted on chromosome ten (PTEN) is associated with malignant progression in many cancers including colorectal cancer (CRC). PTEN is involved in negatively regulating the Phosphatidylinositol 3-kinase (PI3K)/AKT oncogen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chowdhury, Sanjib, Ongchin, Melanie, Wan, Guanghua, Sharratt, Elizabeth, Brattain, Michael G., Rajput, Ashwani
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096772/
https://ncbi.nlm.nih.gov/pubmed/23623571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.03.035
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