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Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells

BACKGROUND: TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS: To test the importance...

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Bibliografiske detaljer
Main Authors: Simms, Neka A K, Rajput, Ashwani, Sharratt, Elizabeth A, Ongchin, Melanie, Teggart, Carol A, Wang, Jing, Brattain, Michael G
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517326/
https://ncbi.nlm.nih.gov/pubmed/22672900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-221
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