Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells

BACKGROUND: TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS: To test the importance...

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Autori principali: Simms, Neka A K, Rajput, Ashwani, Sharratt, Elizabeth A, Ongchin, Melanie, Teggart, Carol A, Wang, Jing, Brattain, Michael G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517326/
https://ncbi.nlm.nih.gov/pubmed/22672900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-221
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