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Intra-Tumoral Heterogeneity in Metastatic Potential and Survival Signaling between Iso-Clonal HCT116 and HCT116b Human Colon Carcinoma Cell Lines

BACKGROUND: Colorectal cancer (CRC) metastasis is a leading cause of cancer-related deaths in the United States. The molecular mechanisms underlying this complex, multi-step pathway are yet to be completely elucidated. Recent reports have stressed the importance of intra-tumoral heterogeneity in the...

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Detalhes bibliográficos
Main Authors: Chowdhury, Sanjib, Ongchin, Melanie, Sharratt, Elizabeth, Dominguez, Ivan, Wang, Jing, Brattain, Michael G., Rajput, Ashwani
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613369/
https://ncbi.nlm.nih.gov/pubmed/23560089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060299
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