Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease

We recently discovered that protein components of the ribonucleic acid (RNA) spliceosome form cytoplasmic aggregates in Alzheimer's disease (AD) brain, resulting in widespread changes in RNA splicing. However, the involvement of small nuclear RNAs (snRNAs), also key components of the spliceosom...

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Autores principales: Hales, Chadwick M., Dammer, Eric B., Diner, Ian, Yi, Hong, Seyfried, Nicholas T., Gearing, Marla, Glass, Jonathan D., Montine, Thomas J., Levey, Allan I., Lah, James J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096308/
https://ncbi.nlm.nih.gov/pubmed/24571648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12133
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