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Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease

We recently discovered that protein components of the ribonucleic acid (RNA) spliceosome form cytoplasmic aggregates in Alzheimer's disease (AD) brain, resulting in widespread changes in RNA splicing. However, the involvement of small nuclear RNAs (snRNAs), also key components of the spliceosom...

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Библиографические подробности
Главные авторы: Hales, Chadwick M., Dammer, Eric B., Diner, Ian, Yi, Hong, Seyfried, Nicholas T., Gearing, Marla, Glass, Jonathan D., Montine, Thomas J., Levey, Allan I., Lah, James J.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096308/
https://ncbi.nlm.nih.gov/pubmed/24571648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12133
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