Aggregates of Small Nuclear Ribonucleic Acids (snRNAs) in Alzheimer's Disease

We recently discovered that protein components of the ribonucleic acid (RNA) spliceosome form cytoplasmic aggregates in Alzheimer's disease (AD) brain, resulting in widespread changes in RNA splicing. However, the involvement of small nuclear RNAs (snRNAs), also key components of the spliceosom...

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Bibliografske podrobnosti
Main Authors: Hales, Chadwick M., Dammer, Eric B., Diner, Ian, Yi, Hong, Seyfried, Nicholas T., Gearing, Marla, Glass, Jonathan D., Montine, Thomas J., Levey, Allan I., Lah, James J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2014
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096308/
https://ncbi.nlm.nih.gov/pubmed/24571648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12133
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