N-Acetylcysteine Prevents Loss of Dopaminergic Neurons in the EAAC(−/−) Mouse

OBJECTIVE: Dopaminergic neuronal death in Parkinson’s disease (PD) is accompanied by oxidative stress and preceded by glutathione depletion. The development of disease-modifying therapies for PD has been hindered by a paucity of animal models that mimic these features and demonstrate an age-related...

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Huvudupphovsmän: Berman, Ari E., Chan, Wai Yee, Brennan, Angela M., Reyes, Reno C., Adler, Brittany L., Suh, Sang Won, Kauppinen, Tiina M., Edling, Ylva, Swanson, Raymond A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096233/
https://ncbi.nlm.nih.gov/pubmed/21446024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22162
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