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Chemically Accessible Hsp90 Inhibitor That Does Not Induce a Heat Shock Response
[Image: see text] Recent cancer therapies have focused on targeting biology networks through a single regulatory protein. Heat shock protein 90 (hsp90) is an ideal oncogenic target as it regulates over 400 client proteins and cochaperones. However, clinical inhibitors of hsp90 have had limited succe...
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| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical
Society
2014
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4094262/ https://ncbi.nlm.nih.gov/pubmed/25050163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500114p |
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