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Regulated Localization Is Sufficient for Hormonal Control of Regulator of G Protein Signaling Homology Rho Guanine Nucleotide Exchange Factors (RH-RhoGEFs)

The regulator of G protein signaling homology (RH) Rho guanine nucleotide exchange factors (RhoGEFs) (p115RhoGEF, leukemia-associated RhoGEF, and PDZ-RhoGEF) contain an RH domain and are specific GEFs for the monomeric GTPase RhoA. The RH domains interact specifically with the α subunits of G(12) he...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Carter, Angela M., Gutowski, Stephen, Sternweis, Paul C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094083/
https://ncbi.nlm.nih.gov/pubmed/24855647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564930
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