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Plasma Membrane Association of p63 Rho Guanine Nucleotide Exchange Factor (p63RhoGEF) Is Mediated by Palmitoylation and Is Required for Basal Activity in Cells

Activation of G protein-coupled receptors at the cell surface leads to the activation or inhibition of intracellular effector enzymes, which include various Rho guanine nucleotide exchange factors (RhoGEFs). RhoGEFs activate small molecular weight GTPases at the plasma membrane (PM). Many of the kno...

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Detalhes bibliográficos
Main Authors: Aittaleb, Mohamed, Nishimura, Akiyuki, Linder, Maurine E., Tesmer, John J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190789/
https://ncbi.nlm.nih.gov/pubmed/21832057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273342
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