Identification of a Novel Prenyl and Palmitoyl Modification at the CaaX Motif of Cdc42 That Regulates RhoGDI Binding

Por Nishimura, Akiyuki, Linder, Maurine E.
Publicado em 2013

Ric-8B Stabilizes the α Subunit of Stimulatory G Protein by Inhibiting Its Ubiquitination

Por Nagai, Yusuke, Nishimura, Akiyuki, Tago, Kenji, Mizuno, Norikazu, Itoh, Hiroshi
Publicado em 2010

Plasma Membrane Association of p63 Rho Guanine Nucleotide Exchange Factor (p63RhoGEF) Is Mediated by Palmitoylation and Is Required for Basal Activity in Cells

Por Aittaleb, Mohamed, Nishimura, Akiyuki, Linder, Maurine E., Tesmer, John J. G.
Publicado em 2011

TRPC3 Channels in Cardiac Fibrosis

Por Numaga-Tomita, Takuro, Oda, Sayaka, Shimauchi, Tsukasa, Nishimura, Akiyuki, Mangmool, Supachoke, Nishida, Motohiro
Publicado no Front Cardiovasc Med (2017)

G protein-coupled receptor signaling through Gq and JNK negatively regulates neural progenitor cell migration

Por Mizuno, Norikazu, Kokubu, Hiroshi, Sato, Maiko, Nishimura, Akiyuki, Yamauchi, Junji, Kurose, Hitoshi, Itoh, Hiroshi
Publicado em 2005

Stimulation of Adenosine A(2B) Receptor Inhibits Endothelin-1-Induced Cardiac Fibroblast Proliferation and α-Smooth Muscle Actin Synthesis Through the cAMP/Epac/PI3K/Akt-Signaling...

Por Phosri, Sarawuth, Arieyawong, Ajaree, Bunrukchai, Kwanchai, Parichatikanond, Warisara, Nishimura, Akiyuki, Nishida, Motohiro, Mangmool, Supachoke
Publicado no Front Pharmacol (2017)

Structural basis for the specific inhibition of heterotrimeric G(q) protein by a small molecule

Por Nishimura, Akiyuki, Kitano, Ken, Takasaki, Jun, Taniguchi, Masatoshi, Mizuno, Norikazu, Tago, Kenji, Hakoshima, Toshio, Itoh, Hiroshi
Publicado em 2010

Divergent Roles of CAAX Motif-signaled Posttranslational Modifications in the Regulation and Subcellular Localization of Ral GTPases

Por Gentry, Leanna R., Nishimura, Akiyuki, Cox, Adrienne D., Martin, Timothy D., Tsygankov, Denis, Nishida, Motohiro, Elston, Timothy C., Der, Channing J.
Publicado no J Biol Chem (2015)

TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

Por Oda, Sayaka, Numaga-Tomita, Takuro, Kitajima, Naoyuki, Toyama, Takashi, Harada, Eri, Shimauchi, Tsukasa, Nishimura, Akiyuki, Ishikawa, Tatsuya, Kumagai, Yoshito, Birnbaumer, Lutz, Nishida, Motohiro
Publicado no Sci Rep (2017)

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis

Por Numaga-Tomita, Takuro, Kitajima, Naoyuki, Kuroda, Takuya, Nishimura, Akiyuki, Miyano, Kei, Yasuda, Satoshi, Kuwahara, Koichiro, Sato, Yoji, Ide, Tomomi, Birnbaumer, Lutz, Sumimoto, Hideki, Mori, Yasuo, Nishida, Motohiro
Publicado no Sci Rep (2016)

TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy

Por Shimauchi, Tsukasa, Numaga-Tomita, Takuro, Ito, Tomoya, Nishimura, Akiyuki, Matsukane, Ryosuke, Oda, Sayaka, Hoka, Sumio, Ide, Tomomi, Koitabashi, Norimichi, Uchida, Koji, Sumimoto, Hideki, Mori, Yasuo, Nishida, Motohiro
Publicado no JCI Insight (2017)

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

Por Kitajima, Naoyuki, Numaga-Tomita, Takuro, Watanabe, Masahiko, Kuroda, Takuya, Nishimura, Akiyuki, Miyano, Kei, Yasuda, Satoshi, Kuwahara, Koichiro, Sato, Yoji, Ide, Tomomi, Birnbaumer, Lutz, Sumimoto, Hideki, Mori, Yasuo, Nishida, Motohiro
Publicado no Sci Rep (2016)

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Por Akaike, Takaaki, Ida, Tomoaki, Wei, Fan-Yan, Nishida, Motohiro, Kumagai, Yoshito, Alam, Md. Morshedul, Ihara, Hideshi, Sawa, Tomohiro, Matsunaga, Tetsuro, Kasamatsu, Shingo, Nishimura, Akiyuki, Morita, Masanobu, Tomizawa, Kazuhito, Nishimura, Akira, Watanabe, Satoshi, Inaba, Kenji, Shima, Hiroshi, Tanuma, Nobuhiro, Jung, Minkyung, Fujii, Shigemoto, Watanabe, Yasuo, Ohmuraya, Masaki, Nagy, Péter, Feelisch, Martin, Fukuto, Jon M., Motohashi, Hozumi
Publicado no Nat Commun (2017)