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Acquired Resistance of Mycobacterium tuberculosis to Bedaquiline
Bedaquiline (BDQ), an ATP synthase inhibitor, is the first drug to be approved for treatment of multi-drug resistant tuberculosis in decades. In vitro resistance to BDQ was previously shown to be due to target-based mutations. Here we report that non-target based resistance to BDQ, and cross-resista...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092087/ https://ncbi.nlm.nih.gov/pubmed/25010492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102135 |
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