Tryptophan Catabolism Restricts IFN-γ-expressing Neutrophils and Clostridium difficile Immunopathology

The interplay between Clostridium difficile and the host's metabolome is believed to influence the severity of infection. However, the mechanism for this phenomenon remains unclear. In this study we model one of these metabolic pathways by focussing on tryptophan metabolism in the host. We foun...

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書誌詳細
主要な著者: El-Zaatari, Mohamad, Chang, Yu-Ming, Zhang, Min, Franz, Matthew, Shreiner, Andrew, McDermott, Andrew J., van der Sluijs, Koenraad F., Lutter, René, Grasberger, Helmut, Kamada, Nobuhiko, Young, Vincent B., Huffnagle, Gary B., Kao, John Y.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091639/
https://ncbi.nlm.nih.gov/pubmed/24935925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302913
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