Aim2-mediated/IFN-β–independent regulation of gastric metaplastic lesions via CD8(+) T cells

Development of gastric cancer is often preceded by chronic inflammation, but the immune cellular mechanisms underlying this process are unclear. Here we demonstrated that an inflammasome molecule, absent in melanoma 2 (Aim2), was upregulated in patients with gastric cancer and in spasmolytic polypep...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: El-Zaatari, Mohamad, Bishu, Shrinivas, Zhang, Min, Grasberger, Helmut, Hou, Guoqing, Haley, Henry, Humphries, Brock, Syu, Li-Jyun, Dlugosz, Andrzej A., Luker, Kathy, Luker, Gary D., Eaton, Kathryn, Kamada, Nobuhiko, Cascalho, Marilia, Kao, John Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141403/
https://ncbi.nlm.nih.gov/pubmed/32053518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94035
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