Aim2-mediated/IFN-β–independent regulation of gastric metaplastic lesions via CD8(+) T cells

Development of gastric cancer is often preceded by chronic inflammation, but the immune cellular mechanisms underlying this process are unclear. Here we demonstrated that an inflammasome molecule, absent in melanoma 2 (Aim2), was upregulated in patients with gastric cancer and in spasmolytic polypep...

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Pubblicato in:JCI Insight
Autori principali: El-Zaatari, Mohamad, Bishu, Shrinivas, Zhang, Min, Grasberger, Helmut, Hou, Guoqing, Haley, Henry, Humphries, Brock, Syu, Li-Jyun, Dlugosz, Andrzej A., Luker, Kathy, Luker, Gary D., Eaton, Kathryn, Kamada, Nobuhiko, Cascalho, Marilia, Kao, John Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141403/
https://ncbi.nlm.nih.gov/pubmed/32053518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94035
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