Increased risk for inflammatory bowel disease in congenital hypothyroidism supports the existence of a shared susceptibility factor

Loss-of-function mutations in dual oxidase (DUOX) 2 are the most common genetic variants found in congenital hypothyroidism (CH), and similar mutations have been recently reported in few very-early-onset inflammatory bowel disease (IBD) patients without CH. If DUOX2 variants indeed increase suscepti...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Grasberger, Helmut, Noureldin, Mohamed, Kao, Timothy D., Adler, Jeremy, Lee, Joyce M., Bishu, Shrinivas, El-Zaatari, Mohamad, Kao, John Y., Waljee, Akbar K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033893/
https://ncbi.nlm.nih.gov/pubmed/29977049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28586-5
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