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The Role of Placental Tryptophan Catabolism

This review discusses the mechanisms and consequences of degradation of tryptophan (Trp) in the placenta, focusing mainly on the role of indoleamine 2,3-dioxygenase-1 (IDO1), one of three enzymes catalyzing the first step of the kynurenine pathway of Trp degradation. IDO1 has been implicated in regu...

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Detalhes bibliográficos
Main Authors: Sedlmayr, Peter, Blaschitz, Astrid, Stocker, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032907/
https://ncbi.nlm.nih.gov/pubmed/24904580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00230
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