A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

APO866, an inhibitor of NAD biosynthesis, exhibits potent antitumor properties in various malignancies. Recently, it has been shown that APO866 induces apoptosis and autophagy in human hematological cancer cells, but the role of autophagy in APO866-induced cell death remains unclear. Here, we report...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ginet, Vanessa, Puyal, Julien, Rummel, Coralie, Aubry, Dominique, Breton, Caroline, Cloux, Anne-Julie, Majjigapu, Somi R, Sordat, Bernard, Vogel, Pierre, Bruzzone, Santina, Nencioni, Alessio, Duchosal, Michel A, Nahimana, Aimable
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2014
Aiheet:
Basic Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091148/
https://ncbi.nlm.nih.gov/pubmed/24487122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27722
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