The cytotoxicity of (–)-lomaiviticin A arises from induction of double-strand breaks in DNA

Lignende værker

• Mechanism of Action Studies of Lomaiviticin A and the Monomeric Lomaiviticin Aglycon. Selective and Potent Activity Toward DNA Double-Strand Break Repair-Deficient Cell Lines
  af: Colis, Laureen C., et al.
  Udgivet: (2015)
• Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821
  af: Colis, Laureen C., et al.
  Udgivet: (2016)
• Synthesis and biological evaluation of (2S,2′S)-lomaiviticin A.
  af: Kaneko, Miho, et al.
  Udgivet: (2021)
• Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A
  af: Woo, Christina M., et al.
  Udgivet: (2016)
• Development of Enantioselective Synthetic Routes to (–)-Kinamycin F and (–)-Lomaiviticin Aglycon
  af: Woo, Christina M., et al.
  Udgivet: (2012)