Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption.

The delivery of viral vectors to the brain for treatment of intracerebral tumors is most commonly accomplished by stereotaxic inoculation directly into the tumor. However, the small volume of distribution by inoculation may limit the efficacy of viral therapy of large or disseminated tumors. We have...

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Main Authors: Nilaver, G, Muldoon, L L, Kroll, R A, Pagel, M A, Breakefield, X O, Davidson, B L, Neuwelt, E A
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC40896/
https://ncbi.nlm.nih.gov/pubmed/7568227
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