Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.

Delivery of adenovirus, herpes simplex virus (HSV), and paramagnetic monocrystalline iron oxide nanoparticles (MION) to rat brain (n = 64) was assessed after intracerebral inoculation or osmotic disruption of the blood-brain barrier (BBB). After intracerebral inoculation, the area of distribution wa...

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Bibliographic Details
Main Authors: Muldoon, L. L., Nilaver, G., Kroll, R. A., Pagel, M. A., Breakefield, X. O., Chiocca, E. A., Davidson, B. L., Weissleder, R., Neuwelt, E. A.
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869962/
https://ncbi.nlm.nih.gov/pubmed/7495307
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