Osmotic blood-brain barrier disruption. Computerized tomographic monitoring of chemotherapeutic agent delivery.

The present study describes a canine model of transient reversible blood-brain barrier disruption with hyperosmolar mannitol infusion into the internal carotid artery. Studies in this model show that osmotic blood-brain barrier disruption before intracarotid infusion of methotrexate results in marke...

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Bibliografiske detaljer
Main Authors: Neuwelt, E A, Maravilla, K R, Frenkel, E P, Rapaport, S I, Hill, S A, Barnett, P A
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC372166/
https://ncbi.nlm.nih.gov/pubmed/457877
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