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A Physiological Barrier Distal to the Anatomic Blood-Brain Barrier in a Model of Transvascular Delivery

BACKGROUND AND PURPOSE: Osmotic disruption of the blood-brain barrier (BBB) provides a method for transvascular delivery of therapeutic agents to the brain. The apparent global delivery of viral-sized iron oxide particles to the rat brain after BBB opening as seen on MR images was compared with the...

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Publicado en:AJNR Am J Neuroradiol
Main Authors: Muldoon, Leslie L., Pagel, Michael A., Kroll, Robert A., Roman-Goldstein, Simon, Jones, Russell S., Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Neuroradiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056106/
https://ncbi.nlm.nih.gov/pubmed/10094341
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