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The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb
The KIX domain is a mediator of the interaction between different transcription factors. This complex function is carried out via two distinct binding sites located on opposite sides of the protein; namely, the ‘c-Myb site’ and the ‘MLL site’, named after their characteristic ligands—the transactiva...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4088980/ https://ncbi.nlm.nih.gov/pubmed/24753318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2480 |
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