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The allosteric communication pathways in KIX domain of CBP

Allosteric regulation plays an important role in a myriad of biomacromolecular processes. Specifically, in a protein, the process of allostery refers to the transmission of a local perturbation, such as ligand binding, to a distant site. Decades after the discovery of this phenomenon, models built o...

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Autors principals: Palazzesi, Ferruccio, Barducci, Alessandro, Tollinger, Martin, Parrinello, Michele
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761601/
https://ncbi.nlm.nih.gov/pubmed/23940332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313548110
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