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Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core

[Image: see text] The KIX domain of the transcriptional coactivator CREB binding protein (CBP) co-operatively mediates interactions between transcription factors. Binding of the transcription factor mixed-lineage leukemia (MLL) induces the formation of a low-populated conformer of KIX that resembles...

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Bibliografiska uppgifter
Huvudupphovsmän: Brüschweiler, Sven, Konrat, Robert, Tollinger, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2013
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719477/
https://ncbi.nlm.nih.gov/pubmed/23651431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4002188
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