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Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system
A classical dogma of molecular biology dictates that the 3D structure of a protein is necessary for its function. However, a considerable fraction of the human proteome, although functional, does not adopt a defined folded state under physiological conditions. These intrinsically disordered proteins...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773806/ https://ncbi.nlm.nih.gov/pubmed/23980173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307337110 |
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