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Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein
Folding and function may impose different requirements on the amino acid sequences of proteins, thus potentially giving rise to conflict. Such a conflict, or frustration, can result in the formation of partially misfolded intermediates that can compromise folding and promote aggregation. We investig...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191818/ https://ncbi.nlm.nih.gov/pubmed/25228761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405233111 |
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