Identification of DW532 as a novel anti-tumor agent targeting both kinases and tubulin

AIM: 7,8-Dihydroxy-4-(3-hydroxy-4-methoxyphenyl)-2H-chromen-2-one (DW532) is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. The aim of this study was to identify DW532 as a agent targeting both kinases and...

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Autors principals: Peng, Ting, Wu, Jian-rui, Tong, Lin-jiang, Li, Meng-yuan, Chen, Fang, Leng, Yi-xin, Qu, Rong, Han, Kun, Su, Yi, Chen, Yi, Duan, Wen-hu, Xie, Hua, Ding, Jian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088284/
https://ncbi.nlm.nih.gov/pubmed/24858311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.33
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