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Halichondrin B amide acts as tubulin binding agent to exhibit anti-tumor efficacy in hematologic cancers
Since microtubule dynamics play an indispensable role in cell division, cell motility, cellular transport, cell polarity and cell signalling, the microtubule appears as a highly attractive target for anticancer drug design. The present study demonstrates the role of halichondrin B amide (HCBA), an a...
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Publicado no: | Int J Clin Exp Med |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
e-Century Publishing Corporation
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4694530/ https://ncbi.nlm.nih.gov/pubmed/26770630 |
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