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Halichondrin B amide acts as tubulin binding agent to exhibit anti-tumor efficacy in hematologic cancers

Since microtubule dynamics play an indispensable role in cell division, cell motility, cellular transport, cell polarity and cell signalling, the microtubule appears as a highly attractive target for anticancer drug design. The present study demonstrates the role of halichondrin B amide (HCBA), an a...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Li, Ying-Chun, Zhang, Rong, Yang, Ying, Li, Jia, Zhu, Ke, Yao, Kun, Liu, Zhuo-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694530/
https://ncbi.nlm.nih.gov/pubmed/26770630
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