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The TREM2 variant p.R47H is a risk factor for sporadic amyotrophic lateral sclerosis
IMPORTANCE: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which microglia play a significant and active role. Recently, a rare missense variant (p.R47H) in the microglial activating gene TREM2 was found to increase the risk of several neurodegenerative diseases, includi...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4087113/ https://ncbi.nlm.nih.gov/pubmed/24535663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.6237 |
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