Frontobasal gray matter loss is associated with the TREM2 p.R47H variant

A rare heterozygous TREM2 variant p.R47H (rs75932628) has been associated with an increased risk for Alzheimer disease (AD). We aimed to investigate the clinical presentation, neuropsychological profile and regional pattern of gray matter and white matter loss associated with the TREM2 variant p.R47...

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Publicado en:Neurobiol Aging
Main Authors: Luis, E.O., Ortega-Cubero, S., Lamet, I., Razquin, C., Cruchaga, C., Benitez, B.A., Lorenzo, E., Irigoyen, J., Pastor, M.A., Pastor, P.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253600/
https://ncbi.nlm.nih.gov/pubmed/25027412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.06.007
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