Frontobasal gray matter loss is associated with the TREM2 p.R47H variant

A rare heterozygous TREM2 variant p.R47H (rs75932628) has been associated with an increased risk for Alzheimer disease (AD). We aimed to investigate the clinical presentation, neuropsychological profile and regional pattern of gray matter and white matter loss associated with the TREM2 variant p.R47...

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Publicat a:Neurobiol Aging
Autors principals: Luis, E.O., Ortega-Cubero, S., Lamet, I., Razquin, C., Cruchaga, C., Benitez, B.A., Lorenzo, E., Irigoyen, J., Pastor, M.A., Pastor, P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253600/
https://ncbi.nlm.nih.gov/pubmed/25027412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.06.007
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