The TREM2 variant p.R47H is a risk factor for sporadic amyotrophic lateral sclerosis

IMPORTANCE: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which microglia play a significant and active role. Recently, a rare missense variant (p.R47H) in the microglial activating gene TREM2 was found to increase the risk of several neurodegenerative diseases, includi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cady, Janet, Koval, Erica D., Benitez, Bruno A., Zaidman, Craig, Jockel-Balsarotti, Jennifer, Allred, Peggy, Baloh, Robert H., Ravits, John, Simpson, Ericka, Appel, Stanley H., Pestronk, Alan, Goate, Alison M., Miller, Timothy M., Cruchaga, Carlos, Harms, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087113/
https://ncbi.nlm.nih.gov/pubmed/24535663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.6237
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados