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Isolated nuclei adapt to force and reveal a mechanotransduction pathway within the nucleus

Mechanical forces influence many aspects of cell behavior. Forces are detected and transduced into biochemical signals by force bearing molecular elements located at the cell surface, in adhesion complexes or in cytoskeletal structures(1). The nucleus is physically connected to the cell surface thro...

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Dettagli Bibliografici
Autori principali: Guilluy, Christophe, Osborne, Lukas D., Van Landeghem, Laurianne, Sharek, Lisa, Superfine, Richard, Garcia-Mata, Rafael, Burridge, Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085695/
https://ncbi.nlm.nih.gov/pubmed/24609268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2927
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