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Isolated nuclei adapt to force and reveal a mechanotransduction pathway within the nucleus
Mechanical forces influence many aspects of cell behavior. Forces are detected and transduced into biochemical signals by force bearing molecular elements located at the cell surface, in adhesion complexes or in cytoskeletal structures(1). The nucleus is physically connected to the cell surface thro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085695/ https://ncbi.nlm.nih.gov/pubmed/24609268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2927 |
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