Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity

Nitric oxide (NO) inhalation has been reported to increase the oxygen affinity of sickle cell erythrocytes. Also, proposed allosteric mechanisms for hemoglobin, based on S-nitrosation of β-chain cysteine 93, raise the possibilty of altering the pathophysiology of sickle cell disease by inhibiting po...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Gladwin, Mark T., Schechter, Alan N., Shelhamer, James H., Pannell, Lewis K., Conway, Deirdre A., Hrinczenko, Borys W., Nichols, James S., Pease-Fye, Margaret E., Noguchi, Constance T., Rodgers, Griffin P., Ognibene, Frederick P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1999
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC408559/
https://ncbi.nlm.nih.gov/pubmed/10510334
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items