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Nitric Oxide Pathology and Therapeutics in Sickle Cell Disease
Sickle cell disease is caused by a mutant form of hemoglobin that polymerizes under hypoxic conditions which leads to red blood cell (RBC) distortion, calcium-influx mediated RBC dehydration, increased RBC adhesivity, reduced RBC deformability, increased RBC fragility, and hemolysis. These impairmen...
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| Publicado no: | Clin Hemorheol Microcirc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911689/ https://ncbi.nlm.nih.gov/pubmed/29614634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CH-189009 |
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