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Effects of nitric oxide and its congeners on sickle red blood cell deformability
BACKGROUND: Sickle cell disease is characterized by hemoglobin (Hb) polymerization upon deoxygenation. Polymerization causes the sickle cells to become rigid and misshapen (sickling). Red blood cell (RBC) dehydration greatly increases polymerization. Cycles of sickling and unsickling cause an influx...
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| Publié dans: | Transfusion |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605849/ https://ncbi.nlm.nih.gov/pubmed/25912054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.13134 |
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